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十三價疫苗有效預防侵入性肺炎球菌病及肺炎球菌引致的非侵入性肺炎;十三價疫苗含13 種莢膜抗原(1、3、4、5、6A、6B、7F、9V、14、18C、19A、19F和23F)。接種十三價肺炎球菌結合疫苗後,常見不良反應包括注射部位可能在接種後短時間內出現輕微腫脹及疼痛,但大部分反應在兩天內會自然消退。有些人可能會出現輕微發熱、疲勞、頭痛、發冷或肌肉疼痛。在針口位置出現嚴重的疼痛或移動手臂困難是非常罕見的。

PCV13 includes 13 capsular antigens (1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F and 23F). Common adverse reactions after PCV13 administration include slight swelling and tenderness at the injection site shortly following injection but most resolve within two days. Some may experience mild fever, fatigue, headache, chills, or muscle pain. Severe pain or difficulty in moving the arm where the shot was given was very rare.